I suffer from chronic pain from my neck to my tailbone as well as 2 reconstructive ankles, left knee replacement, and Combat PTSD, Kuwait/Iraq/Somalia War conflicts. This Hybrid works perfect for me in that it eases my chronic pain, muscle spasms, and mentally really puts me in a happy-go-lucky feeling. My insomnia is definitely gone and my appetite has stayed pretty steady in that I'm eating more on a regular basis. That is how it works "medically" for me!